F30A Journal — Chronic Pain

Introduction Cannabigerol (CBG), a non-psychoactive cannabinoid found in the Cannabis sativa plant, is gaining attention in the scientific community for its potential therapeutic benefits. Unlike its more famous counterparts, THC and CBD, CBG is often referred to as the "mother of all cannabinoids" due to a common misconception about its role as a precursor from which other cannabinoids are synthesized (these cannabinoids are synthesized from CBGA, the acidic form of CBG, from which CBG is itself synthesized). This article delves into the effects, benefits, and legal status of CBG, with a particular focus on its interaction with various receptor sites...

The endocannabinoid system (ECS) is a complex signaling network of receptors, enzymes, and endocannabinoids that helps regulate various physiological processes, including reproduction. The ECS is composed of cannabinoid receptors (CB₁, CB₂, and GPR55 are the most common), endogenous ligands (endocannabinoids), and enzymes responsible for endocannabinoid synthesis and degradation. Recent research has highlighted the significant impact of the ECS on the female reproductive system, affecting fertility, pregnancy, and other reproductive functions. Endocannabinoids are naturally occurring molecules that bind to cannabinoid receptors in the body, including CB₁ and CB₂ receptors. CB₁ receptors are highly expressed in the female reproductive system, including the...

Given the wide range of cannabidiol’s potential therapeutic benefits, there are consequently nearly as many ways to formulate a product to address patients’ needs. Topical applications, in particular, provide excellent support to orally ingested CBD capsules for targeted symptom relief. Formula30A’s recently released CBD Infused Balm is all natural, and contains the same premium quality full spectrum cannabinoids as our CBD capsules - (It’s now available in an easy-to-use twist-up applicator - see the new look in the Provider Store).We asked our community of Medical Providers how they are implementing Formula30A Balm into their practices, and the treatment protocols they...

­As body systems go, the endocannabinoid system (ECS) is an infant, having been discovered in the waning decades of the twentieth century. For over a hundred years, science had been trying to isolate the mysteries of cannabis. Cannabidiol (CBD) was the first natural cannabinoid to be isolated from the cannabis plant, but it was soon found not to be the primary psychoactive ingredient. It would be another 30 years before ∆9-tetrahydrocannabinol (THC) was isolated, and the rest, as they say, was history.The discovery of the cannabinoid receptors CB-1 and CB-2 in mammals, and the subsequent recognition of the ECS as...